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Dynamic Histone Methylation and Chromatin Organization in Tumor Suppression

March 31–April 3, 2022

Original Dates: March 4–7, 2021

Chaired By

 Kimryn Rathmell, MD, PhD, Vanderbilt University
 Brian D. Strahl, PhD, University of North Carolina

Important Dates

 01/31/2022 -  Travel Form Due
 02/28/2022 -  Abstracts Due

Travel Agent Information

 Meeting #: Refer to your packet.
 Hours: 8:00am – 8:00 pm EST M-F
 Domestic: 669-210-8002
 International : 623-516-6140

Venue Information

Evins Mill
1535 Evins Mill Road
Smithville, TN 37166

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Program Description

A multitude of activities and functions have arisen around the enzymes that provide specific methylation marks on histones, and which are perturbed in cancer. These enzymes, for example SETD2, are no longer considered as simple factors in the specificities of methylation. Recent data suggests that spatial distribution, dynamic activity, structural composition, as well as non-histone targets adds to the complexity of these interactions as they pertain to cancer. The recent explosion of mutations in the histone tail residues as well as methyltransferase domain mutants has led to potential for siloing as the field grapples with the diverse functions of these proteins. A meeting of this nature has potential to advance the science of histone biology in cancer suppression and to bridge in the many additional targets and factors involved, bringing investigators approaching this problem from a diverse array of angles.

Forum Participants

Participant Institution
Mark T. Bedford, PhD MD Anderson Cancer Center
Or Gozani, MD, PhD Stanford University
Florian Grebien, PhD Institute of Medical Biochemistry, University of Veterinary Medicine Vienna
Cigall Kadoch, PhD Dana-Farber Cancer Institute
Tatiana Kutateladze, PhD University of Colorado
Peter W. Lewis, PhD University of Wisconsin
Matthew Lorincz, PhD University of British Columbia
Janet Partridge, PhD St. Jude Children's Research Hospital
Kimryn Rathmell, MD PhD Vanderbilt Ingram-Cancer Center
Brian Strahl, PhD University of North Carolina
Samra Turajlic, PhD The Francis Crick Institute
Christopher Vakoc, MD, PhD Cold Spring Harbor Laboratory
Cheryl Walker, PhD Baylor College of Medicine
Jerry Workman, PhD Stowers Institute for Medical Research

Forum Scholars

Scholar Institution
Aguirre de Cubas, PhD Vanderbilt University Medical Center
Charles Ishak, PhD Princess Margaret Cancer Centre, University Health Network
Michael Meers, PhD Fred Hutchinson Cancer Research Center

Airport Information

Nashville's International Airport (BNA) is the preferred airport as it is only 60 minutes from the meeting location.

  • Arrivals - Thursday at 1 PM, 3 PM and 5 PM
  • Departures - Sunday at 10 AM and 12 PM

Submit Travel Form


The abstracts should be only one or two paragraphs outlining the theme of your presentation and should reflect the objective and spirit of the meeting (see above). Abstracts will be circulated about one week before the meeting. The meeting organizer will start requesting them a month before the meeting.

Submit Abstract

For more than 30 years, the Forbeck Foundation has proven to be an excellent steward of donor funds and has remained focused on executing its mission. Interested in sponsoring this Forum? Contact us today for more information!