Navdeep Chandel, PhD of Northwestern University
Heather Christofk, PhD, UCLA
Jason Locasale, PhD, Duke University
Asilomar Conference Grounds
800 Asilomar Avenue
Pacific Grove, CA 93950
Meeting #: Refer to your packet.
Hours: 8:00am – 8:00 pm EST M-F
International : 623-516-6140
Nutrition exerts profound effects on health, and dietary interventions are commonly used to treat diseases of metabolic etiology. Although cancer has a substantial metabolic component, the development of principles that define whether nutrition and new metabolic therapies may be used to influence tumor outcome are in the beginning stages. Nevertheless, it is also established that targeting metabolic pathways with longstanding chemotherapy agents or radiation can sometimes lead to controlled therapeutic outcomes. In contrast, whether specific dietary interventions could influence the metabolic pathways that are targeted in standard cancer therapies is not well known. Now, recent work has emerged showing that changes in caloric intake, macronutrient composition, and the balance of specific macronutrients in the diet also influence cancer.
For example, a diet high in fat and low carbohydrates can affect the outcome of tumors with defined mechanisms of dysregulated insulin signaling. We and others have shown that changes to the amino acid content in diets can influence metabolism related to the uptake of that nutrient in the tumor which in turn affects cancer outcomes by affecting the metabolic flux in a tumor-specific vulnerable metabolic pathway. Thus, there are emerging studies and mechanism linking nutrition and diet to cancer biology and therapy.
We propose to organize a Focus Meeting that brings together current and emerging leaders whose work bridges the nutrition-cancer interface to discuss their work in the new interdisciplinary field of ‘Nutrition and Cancer Metabolism’ and to explore its potential as a novel area for therapeutic intervention. We aim to bring together scientists who bring diverse perspectives to the table to discuss key questions in the field and identify important future directions.
|Yasmine Belkaid, PhD||National Institutes of Health|
|Lewis Cantley, PhD||Weill Cornell|
|Navdeep Chandel, PhD||Northwestern University|
|Heather Christofk, PhD||University of California, Los Angeles|
|Chi Dang, MD, PhD||The Wistar Institute|
|Ralph Deberardinis, MD, PhD||UT Southwestern|
|Lydia Finley, PhD||Memorial Sloan Kettering Cancer Center|
|Cholsoon Jang, PhD||University of California Irvine|
|Russell Jones, PhD||Van Andel Institute|
|Sue Kaech, PhD||Salk Institute|
|Ernst Lengyel, MD, PhD||University of Chicago|
|Jason Locasale, PhD||Duke University|
|Lydia Lynch, PhD||Harvard Medical School|
|Thales Papagiannakopoulos, PhD||NYU Langone|
|Kathrin Plath, PhD||University of California Los Angeles|
|David Sabatini, MD, PhD||MIT / Whitehead Institute|
|Karen Vousden, PhD||The Francis Crick Institute|
|Kathryn Wellen, PhD||University of Pennsylvania|
|Eileen White, PhD||Rutgers Cancer Institute|
The Monterey Regional Airport (MRY) is the preferred airport as it is only 20 minutes from the meeting location.
Mineta San Jose International (SJC) is 1 1/2 hours from the meeting location without traffic. The Foundation can only accommodate 1 pick up per day at San Jose. If you absolutely must fly into San Jose (ie: International Flights) the Foundation will have the following pick up times:
San Francisco International Airport (SFO) is 2 hours from the meeting location without traffic. The Foundation can only accommodate 1 pick up per day at San Francisco. If you absolutely must fly into San Francisco (ie: International Flights) the Foundation will have the following pick up times:
The abstracts should be only one or two paragraphs outlining the theme of your presentation and should reflect the objective and spirit of the meeting (see above). Abstracts will be circulated about one week before the meeting. The meeting organizer will start requesting them a month before the meeting.Submit Abstract
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