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Diet and Metabolic Therapeutics in Cancer

February 3–6, 2022

Original Dates: April 22–25, 2021


Chaired By

 Navdeep Chandel, PhD of Northwestern University
 Heather Christofk, PhD, UCLA
 Jason Locasale, PhD, Duke University


Important Dates

 11/3/2021 -  Travel Form Due
 12/3/2021 -  Abstracts Due


Travel Agent Information

 Meeting #: Refer to your packet.
 Hours: 8:00am – 8:00 pm EST M-F
 Domestic: 669-210-8002
 International : 623-516-6140


Venue Information

Asilomar Conference Grounds
800 Asilomar Avenue
Pacific Grove, CA 93950
831.372.8016

www.visitasilomar.com


About the Forbeck Foundation

 Forbeck Forum Information
 Travel Information
 General Program
 Frequently Asked Questions
 How to donate to WGFRF


Program Description

Nutrition exerts profound effects on health, and dietary interventions are commonly used to treat diseases of metabolic etiology. Although cancer has a substantial metabolic component, the development of principles that define whether nutrition and new metabolic therapies may be used to influence tumor outcome are in the beginning stages. Nevertheless, it is also established that targeting metabolic pathways with longstanding chemotherapy agents or radiation can sometimes lead to controlled therapeutic outcomes. In contrast, whether specific dietary interventions could influence the metabolic pathways that are targeted in standard cancer therapies is not well known. Now, recent work has emerged showing that changes in caloric intake, macronutrient composition, and the balance of specific macronutrients in the diet also influence cancer.

For example, a diet high in fat and low carbohydrates can affect the outcome of tumors with defined mechanisms of dysregulated insulin signaling. We and others have shown that changes to the amino acid content in diets can influence metabolism related to the uptake of that nutrient in the tumor which in turn affects cancer outcomes by affecting the metabolic flux in a tumor-specific vulnerable metabolic pathway. Thus, there are emerging studies and mechanism linking nutrition and diet to cancer biology and therapy.

We propose to organize a Focus Meeting that brings together current and emerging leaders whose work bridges the nutrition-cancer interface to discuss their work in the new interdisciplinary field of ‘Nutrition and Cancer Metabolism’ and to explore its potential as a novel area for therapeutic intervention. We aim to bring together scientists who bring diverse perspectives to the table to discuss key questions in the field and identify important future directions.


Forum Participants

Participant Institution
Yasmine Belkaid, PhD National Institutes of Health
Lewis Cantley, PhD Weill Cornell
Navdeep Chandel, PhD Northwestern University
Heather Christofk, PhD University of California, Los Angeles
Chi Dang, MD, PhD The Wistar Institute
Ralph Deberardinis, MD, PhD UT Southwestern
Lydia Finley, PhD Memorial Sloan Kettering Cancer Center
Cholsoon Jang, PhD University of California Irvine
Russell Jones, PhD Van Andel Institute
Sue Kaech, PhD Salk Institute
Ernst Lengyel, MD, PhD University of Chicago
Jason Locasale, PhD Duke University
Lydia Lynch, PhD Harvard Medical School
Thales Papagiannakopoulos, PhD NYU Langone
Kathrin Plath, PhD University of California Los Angeles
David Sabatini, MD, PhD MIT / Whitehead Institute
Karen Vousden, PhD The Francis Crick Institute
Kathryn Wellen, PhD University of Pennsylvania
Eileen White, PhD Rutgers Cancer Institute

Forum Scholars

Scholar Institution
Robert Banh, PhD New York University
Ana Patricia Da Silva Gomes, PhD H. Lee Moffitt Cancer Center
Alison Ringel, PhD Harvard Medical School

Airport Information

The Monterey Regional Airport (MRY) is the preferred airport as it is only 20 minutes from the meeting location.

  • Arrivals - Thursday at 1 PM, 3 PM and 5 PM
  • Departures - Sunday at 10 AM, 12 PM and 2 PM

Mineta San Jose International (SJC) is 1 1/2 hours from the meeting location without traffic. The Foundation can only accommodate 1 pick up per day at San Jose. If you absolutely must fly into San Jose (ie: International Flights) the Foundation will have the following pick up times:

  • Arrivals - Thursday at 4 PM
  • Departures - Sunday at 10 AM

San Francisco International Airport (SFO) is 2 hours from the meeting location without traffic. The Foundation can only accommodate 1 pick up per day at San Francisco. If you absolutely must fly into San Francisco (ie: International Flights) the Foundation will have the following pick up times:

  • Arrivals - Thursday at 3 PM
  • Departures - Sunday at 10 AM

Submit Travel Form

Abstracts

The abstracts should be only one or two paragraphs outlining the theme of your presentation and should reflect the objective and spirit of the meeting (see above). Abstracts will be circulated about one week before the meeting. The meeting organizer will start requesting them a month before the meeting.

Submit Abstract

For more than 30 years, the Forbeck Foundation has proven to be an excellent steward of donor funds and has remained focused on executing its mission. Interested in sponsoring this Forum? Contact us today for more information!